Gastroesophageal adenocarcinomas have a poor prognosis. However, numerous randomized clinical trials (RCT) have reviewed, and continue to evaluate, the survival benefit of various therapy regimens. Surgery remains standard care for early stage esophageal cancer and gastric cancer. However, RCTs have plus shown a survival benefit linked to chemotherapy and chemoradiation. Few studies have examined community-based patterns of care for these cancers. A study of esophageal adenocarcinoma and squamous cell carcinoma patients diagnosed amoung 1996 and 1999 observed that chemoradiation without surgery was most frequent treatment, eventhough patients given chemoradiation followed by surgery had better survival in comparison to chemoradiation alone. Research suggests community-based use of therapy and the observed survival of patients in the community can vary depending on clinical and non-clinical factors……..

Original post by Heather Craven

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